STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_0976Cystathionine gamma-lyase; PFAM: aminotransferase, class V; Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: tfu:Tfu_0440 cystathionine gamma-synthase. (387 aa)    
Predicted Functional Partners:
Noca_0939
KEGG: rha:RHA1_ro05843 probable cystathionine beta-synthase; TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
 
 0.993
Noca_2631
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.978
Noca_4307
TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mpa:MAP2123 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.967
Noca_0979
L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; amino acid-binding ACT domain protein; KEGG: sco:SCO4962 threonine dehydratase.
 
 
 0.965
Noca_1627
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mta:Moth_2000 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
 0.957
Noca_4578
Aminotransferase, class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; KEGG: rha:RHA1_ro08885 probable aminotransferase.
 
 
 0.952
Noca_2351
PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: sco:SCO6102 putative nitrite/sulphite reductase.
  
 0.949
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
 
  
 0.947
Noca_3629
KEGG: bcl:ABC0432 O-acetylhomoserine (thiol)-lyase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
 
 
0.939
Noca_3793
PFAM: thiamineS protein; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: pai:PAE2577 ferredoxin-nitrite reductase.
  
 0.931
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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