STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1237KEGG: mmc:Mmcs_4352 ATP dependent DNA ligase. (304 aa)    
Predicted Functional Partners:
Noca_1235
PFAM: ATP dependent DNA ligase; KEGG: fal:FRAAL4382 hypothetical protein.
  
 0.999
Noca_0907
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sma:SAV1697 putative DNA ligase.
   
 0.979
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.966
Noca_2856
DNA primase-like protein; KEGG: sth:STH1795 hypothetical protein.
  
  
 
0.922
Noca_2271
PFAM: ATP dependent DNA ligase; KEGG: sma:SAP1p90 putative ATP-dependint DNA ligase.
   
 0.859
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.780
Noca_1236
KEGG: sma:SAV6775 secreted protein.
       0.773
Noca_1238
Hypothetical protein.
       0.470
Noca_1965
PFAM: protein of unknown function DUF72; KEGG: rha:RHA1_ro02437 hypothetical protein.
 
    0.417
Noca_0728
KEGG: mmc:Mmcs_1279 hypothetical protein.
 
     0.408
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.