STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1249KEGG: cdi:DIP0741 hypothetical protein. (84 aa)    
Predicted Functional Partners:
Noca_1247
Conserved carboxylase region; PFAM: pyruvate carboxyltransferase; Conserved carboxylase region; KEGG: sus:Acid_6961 conserved carboxylase region.
 
  
  0.986
Noca_1248
PFAM: carboxyl transferase; KEGG: cdi:DIP0740 methylmalonyl-CoA decarboxylase, alpha-subunit.
    
 0.981
Noca_1250
PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: cdi:DIP0742 putative decarboxylase.
 
  
  0.973
Noca_4626
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0348 methylmalonate-semialdehyde dehydrogenase.
     
  0.900
Noca_0198
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; KEGG: sil:SPO1469 3-ketosteroid dehydrogenase, putative.
     
  0.800
Noca_0203
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: bbr:BB3064 hypothetical protein.
     
  0.800
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
     
  0.800
Noca_0536
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sma:SAV4876 2-oxoglutarate ferredoxin oxidoreductase, beta subunit.
     
  0.800
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
     
  0.800
Noca_0860
PFAM: AMP-dependent synthetase and ligase; KEGG: rxy:Rxyl_1704 AMP-dependent synthetase and ligase.
     
  0.800
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.