STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1507Two component transcriptional regulator, AraC family; PFAM: ThiJ/PfpI domain protein; KEGG: bca:BCE_2883 hypothetical protein. (191 aa)    
Predicted Functional Partners:
Noca_1506
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: rha:RHA1_ro02936 probable formyl-CoA transferase; Belongs to the CoA-transferase III family.
       0.572
Noca_1508
PFAM: UvrD/REP helicase; KEGG: sco:SCO5183 ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily.
     
 0.561
Noca_1509
PFAM: UvrD/REP helicase; KEGG: fra:Francci3_3799 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily.
     
 0.561
Noca_3207
PFAM: isochorismatase hydrolase; KEGG: eca:ECA2383 putative isochorismatase.
 
    0.476
Noca_2078
PFAM: isochorismatase hydrolase; KEGG: cps:CPS_1616 isochorismatase family protein.
 
    0.469
Noca_0576
Protein of unknown function DUF1486; PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; protein of unknown function DUF1486; KEGG: nfa:nfa29880 hypothetical protein.
 
    0.464
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 
 0.452
Noca_0201
PFAM: isochorismatase hydrolase; KEGG: bur:Bcep18194_C7071 isochorismatase hydrolase.
 
    0.433
Noca_1852
PFAM: NmrA family protein; KEGG: nfa:nfa29880 hypothetical protein.
 
    0.428
Noca_1510
Hypothetical protein.
       0.417
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (30%) [HD]