STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1522PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: nfa:nfa41810 hypothetical protein. (378 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.941
Noca_2659
PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: sma:SAV6714 putative 5'-3' exonuclease.
  
 0.887
Noca_0907
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sma:SAV1697 putative DNA ligase.
 
 0.860
lig
DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
 
 0.822
Noca_1079
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: tfu:Tfu_0258 AP endonuclease, family 1:exodeoxyribonuclease III xth.
   
 0.817
Noca_2271
PFAM: ATP dependent DNA ligase; KEGG: sma:SAP1p90 putative ATP-dependint DNA ligase.
 
 0.808
Noca_2842
PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: mmc:Mmcs_3011 DNA polymerase I.
   
 0.783
Noca_1235
PFAM: ATP dependent DNA ligase; KEGG: fal:FRAAL4382 hypothetical protein.
 
 0.774
Noca_1001
PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: mfa:Mfla_1382 beta-lactamase-like protein.
    
 0.746
Noca_1523
PFAM: protein of unknown function DUF45; KEGG: sco:SCO5194 hypothetical protein.
       0.712
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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