STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1580PFAM: TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein; KEGG: mmc:Mmcs_1430 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein. (1797 aa)    
Predicted Functional Partners:
Noca_1516
ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: sco:SCO5188 putative ATP-dependent DNA helicase.
  
 
 0.953
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.896
Noca_4657
DnaB domain protein helicase, C-terminal domain protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 0.895
Noca_3128
DNA polymerase III, epsilon subunit; KEGG: fal:FRAAL5108 putative DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Excinuclease ABC, C subunit domain protein; UvrB/UvrC protein; Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.
   
 
 0.867
Noca_1572
KEGG: sco:SCO6878 ATP-binding protein.
 
   
 0.829
Noca_2243
KEGG: sco:SCO6878 ATP-binding protein.
 
   
 0.829
Noca_1576
Type IV secretory pathway VirD4 components-like protein; KEGG: sma:SAV4509 conjugative transfer gene complex protein.
 
   
 0.816
Noca_2246
Type IV secretory pathway VirD4 components-like protein; KEGG: fra:Francci3_2361 putative membrane protein.
 
   
 0.816
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.813
Noca_1570
KEGG: fal:FRAAL0037 hypothetical protein; putative membrane protein.
 
    0.772
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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