| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Noca_0496 | Noca_0497 | Noca_0496 | Noca_0497 | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.998 |
| Noca_0496 | Noca_1656 | Noca_0496 | Noca_1656 | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | 0.675 |
| Noca_0496 | Noca_2600 | Noca_0496 | Noca_2600 | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6796 uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase. | 0.997 |
| Noca_0496 | hemC | Noca_0496 | Noca_0495 | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| Noca_0496 | nadE | Noca_0496 | Noca_2044 | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.673 |
| Noca_0497 | Noca_0496 | Noca_0497 | Noca_0496 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | 0.998 |
| Noca_0497 | Noca_1656 | Noca_0497 | Noca_1656 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | 0.787 |
| Noca_0497 | Noca_2600 | Noca_0497 | Noca_2600 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6796 uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase. | 0.932 |
| Noca_0497 | hemC | Noca_0497 | Noca_0495 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.999 |
| Noca_0497 | nadE | Noca_0497 | Noca_2044 | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.470 |
| Noca_0500 | Noca_1656 | Noca_0500 | Noca_1656 | PFAM: Phosphoglycerate mutase; KEGG: sma:SAV4796 phosphoglycerate mutase. | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | 0.673 |
| Noca_1654 | Noca_1655 | Noca_1654 | Noca_1655 | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: cjk:jk0549 putative lipase/esterase LipN. | PFAM: carbohydrate kinase, FGGY; KEGG: mxa:MXAN_2879 putative xylulokinase. | 0.787 |
| Noca_1654 | Noca_1656 | Noca_1654 | Noca_1656 | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: cjk:jk0549 putative lipase/esterase LipN. | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | 0.795 |
| Noca_1654 | Noca_1657 | Noca_1654 | Noca_1657 | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: cjk:jk0549 putative lipase/esterase LipN. | Transcriptional regulator, CdaR family; KEGG: fra:Francci3_3797 hypothetical protein. | 0.533 |
| Noca_1655 | Noca_1654 | Noca_1655 | Noca_1654 | PFAM: carbohydrate kinase, FGGY; KEGG: mxa:MXAN_2879 putative xylulokinase. | PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: cjk:jk0549 putative lipase/esterase LipN. | 0.787 |
| Noca_1655 | Noca_1656 | Noca_1655 | Noca_1656 | PFAM: carbohydrate kinase, FGGY; KEGG: mxa:MXAN_2879 putative xylulokinase. | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | 0.935 |
| Noca_1655 | Noca_1657 | Noca_1655 | Noca_1657 | PFAM: carbohydrate kinase, FGGY; KEGG: mxa:MXAN_2879 putative xylulokinase. | Transcriptional regulator, CdaR family; KEGG: fra:Francci3_3797 hypothetical protein. | 0.531 |
| Noca_1655 | Noca_3184 | Noca_1655 | Noca_3184 | PFAM: carbohydrate kinase, FGGY; KEGG: mxa:MXAN_2879 putative xylulokinase. | Fructose PTS system EIIBC or EIIC component; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit; KEGG: mmc:Mmcs_0080 phosphotransferase system, fructose IIC component; TC 4.A.2.1.4; TC 4.A.2.1.4; TC 4.A.2.1.4. | 0.579 |
| Noca_1656 | Noca_0496 | Noca_1656 | Noca_0496 | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase. | 0.675 |
| Noca_1656 | Noca_0497 | Noca_1656 | Noca_0497 | Aminotransferase; PFAM: class II aldolase/adducin family protein; aminotransferase class-III; KEGG: psp:PSPPH_2738 glutamate-1-semialdehyde aminotransferase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: sma:SAV4742 putative 5-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.787 |