Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_1945KEGG: fra:Francci3_1281 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; Belongs to the dGTPase family. Type 2 subfamily. (423 aa)    
Predicted Functional Partners:
Noca_1242
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sco:SCO2843 putative N-acetylglucosamine-6-phosphate deacetylase; Belongs to the HAD-like hydrolase superfamily.
   
 
  0.914
Noca_1513
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: oih:OB2345 purine nucleoside phosphorylase.
     
 0.903
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.903
Noca_3521
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.902
Noca_2321
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family.
    
  0.900
Noca_2322
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease.
     
  0.900
Noca_1947
KEGG: pac:PPA0957 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Hedgehog/intein hint domain protein; Toprim sub domain protein; DNA primase DnaG, DnaB-binding.
 
   
 0.655
recO
DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
   
 0.568
Noca_1946
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: sma:SAV2735 dehydrogenase.
  
    0.560
Noca_1944
Hypothetical protein.
       0.559
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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