STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1995PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_3758 AMP-dependent synthetase and ligase. (541 aa)    
Predicted Functional Partners:
Noca_1996
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sco:SCO2369 thiol-specific antioxidant protein.
       0.685
Noca_0860
PFAM: AMP-dependent synthetase and ligase; KEGG: rxy:Rxyl_1704 AMP-dependent synthetase and ligase.
 
 
0.608
Noca_0437
PFAM: acyl-CoA oxidase domain protein; acyl-CoA dehydrogenase domain protein; KEGG: tfu:Tfu_2239 hypothetical protein.
 
 
 0.601
Noca_2766
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sma:SAV6197 putative oxidoreductase.
  
 0.557
Noca_2141
PFAM: alpha/beta hydrolase fold; KEGG: rha:RHA1_ro04540 4,9-DSHA hydrolase.
   
 0.547
Noca_2775
PFAM: alpha/beta hydrolase fold; KEGG: nfa:nfa4730 putative hydrolase.
   
 0.547
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
0.533
Noca_1994
KEGG: mmc:Mmcs_3360 hypothetical protein.
       0.530
rplF
LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
 0.518
Noca_1894
PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_3602 AMP-dependent synthetase and ligase.
 
  
 0.505
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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