STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_1998TIGRFAM: HAD-superfamily hydrolase, subfamily IB (PSPase-like); HAD-superfamily subfamily IB hydrolase, TIGR01490; PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain; KEGG: fal:FRAAL3759 putative fatty acyl coA reductase. (799 aa)    
Predicted Functional Partners:
Noca_2000
KEGG: rxy:Rxyl_2107 hypothetical protein.
 
     0.946
Noca_2001
PFAM: phospholipid/glycerol acyltransferase; KEGG: fra:Francci3_2279 phospholipid/glycerol acyltransferase.
 
 0.934
Noca_1999
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rxy:Rxyl_2111 alcohol dehydrogenase, zinc-binding protein.
 
  
 0.877
hisA
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; KEGG: tfu:Tfu_1155 bifunctional HisA/TrpF; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis.
  
  
 0.741
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
  
  
 0.708
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
  
  
 0.684
hisB
PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: blo:BL1297 imidazoleglycerol-phosphate dehydratase.
  
  
 0.668
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
  
  
 0.663
Noca_1669
Diacylglycerol O-acyltransferase; PFAM: condensation domain protein; protein of unknown function UPF0089; KEGG: sru:SRU_2506 uncharacterized protein family (UPF0089).
  
  
 0.625
Noca_2792
Diacylglycerol O-acyltransferase; PFAM: protein of unknown function UPF0089; KEGG: rha:RHA1_ro06855 hypothetical protein; Belongs to the long-chain O-acyltransferase family.
  
  
 0.621
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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