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Noca_2038 protein (Nocardioides sp. JS614) - STRING interaction network
"Noca_2038" - Methionine aminopeptidase in Nocardioides sp. JS614
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Noca_2038Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (275 aa)    
Predicted Functional Partners:
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3’-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (223 aa)
 
 
  0.830
rplD
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel (259 aa)
   
 
  0.796
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (278 aa)
 
 
  0.787
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (338 aa)
   
   
  0.781
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (527 aa)
   
   
  0.758
rplO
50S ribosomal protein L15; Binds to the 23S rRNA (146 aa)
   
 
  0.744
rplQ
50S ribosomal protein L17 (202 aa)
 
   
  0.739
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (289 aa)
 
 
  0.725
tsf
Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (270 aa)
 
   
  0.717
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs (198 aa)
   
 
  0.716
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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