Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_2055PFAM: Hydratase/decarboxylase; KEGG: mxa:MXAN_0925 putative 4-oxalocrotonate decarboxylase. (259 aa)    
Predicted Functional Partners:
Noca_2151
PFAM: Hydratase/decarboxylase; KEGG: rha:RHA1_ro08085 2-oxopent-4-enoate hydratase.
  
  
 
0.923
Noca_2779
PFAM: Hydratase/decarboxylase; KEGG: rha:RHA1_ro08085 2-oxopent-4-enoate hydratase.
  
  
 
0.921
Noca_1651
PFAM: Hydratase/decarboxylase; KEGG: nfa:nfa33180 putative hydratase.
  
  
 
0.920
Noca_1650
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.904
Noca_2150
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
  
 0.904
Noca_1649
Pyruvate carboxyltransferase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.840
Noca_2149
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
  
 0.840
Noca_2053
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: nfa:nfa20320 hypothetical protein.
     
 0.790
Noca_2054
PFAM: phospholipase/Carboxylesterase; KEGG: nph:NP0926A hypothetical protein.
       0.773
Noca_2778
KEGG: rha:RHA1_ro05800 acetaldehyde dehydrogenase (acetylating).
 
  
 0.656
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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