Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_2092PFAM: aldehyde dehydrogenase; KEGG: sma:SAV7177 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)    
Predicted Functional Partners:
Noca_2363
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: mmc:Mmcs_3405 alcohol dehydrogenase GroES-like protein.
  
 0.920
Noca_3322
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pto:PTO1249 alcohol dehydrogenase.
  
 0.920
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.917
Noca_0860
PFAM: AMP-dependent synthetase and ligase; KEGG: rxy:Rxyl_1704 AMP-dependent synthetase and ligase.
  
 0.917
Noca_4175
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mpa:MAP3255 pyruvate decarboxylase; Belongs to the TPP enzyme family.
  
 0.913
Noca_3634
PFAM: aldehyde dehydrogenase; KEGG: mpa:MAP2338 hypothetical protein.
  
  
 
0.911
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.906
Noca_1650
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
    
 0.905
Noca_2150
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
    
 0.905
Noca_3529
PFAM: aldehyde dehydrogenase; KEGG: sco:SCO4913 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.905
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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