STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2152Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rha:RHA1_ro04549 transcriptional regulator, LysR family. (318 aa)    
Predicted Functional Partners:
Noca_2149
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
  
  
 0.604
Noca_2150
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
       0.590
Noca_2151
PFAM: Hydratase/decarboxylase; KEGG: rha:RHA1_ro08085 2-oxopent-4-enoate hydratase.
       0.590
Noca_3022
PFAM: glutamine amidotransferase, class-II; glutamate synthase, alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: sco:SCO2026 putative glutamate synthase large subunit.
  
  
 0.575
Noca_2154
PFAM: Integrase, catalytic region; KEGG: mmc:Mmcs_3191 integrase, catalytic region.
  
  
 0.530
Noca_2153
PFAM: transposase IS3/IS911 family protein; KEGG: mmc:Mmcs_3190 transposase IS3/IS911.
       0.526
Noca_0834
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mmc:Mmcs_1374 transcriptional regulator, LysR family.
  
     0.518
Noca_1012
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: mmc:Mmcs_1366 transcriptional regulator, LysR family.
  
     0.518
Noca_0392
Transcriptional regulator, LysR family; PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: csa:Csal_1417 transcriptional regulator, LysR family.
  
     0.402
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.