Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_21593-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: rpb:RPB_2122 3-hydroxyisobutyrate dehydrogenase. (308 aa)    
Predicted Functional Partners:
Noca_4626
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0348 methylmalonate-semialdehyde dehydrogenase.
 
 
 0.932
Noca_4475
PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: pae:PA2199 probable dehydrogenase.
  
  
 
0.927
Noca_3529
PFAM: aldehyde dehydrogenase; KEGG: sco:SCO4913 putative aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.916
Noca_3634
PFAM: aldehyde dehydrogenase; KEGG: mpa:MAP2338 hypothetical protein.
  
 
 0.916
Noca_0645
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: mmc:Mmcs_2274 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Noca_3205
TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: rha:RHA1_ro05598 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
Noca_2127
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: nfa:nfa10390 putative enoyl-CoA hydratase/isomerase family protein.
  
 0.887
Noca_0148
Carbamoyl-phosphate synthase L chain, ATP-binding protein; PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: rso:RSc0265 probable acyl-CoA carboxylase alpha chain protein.
  
 
 0.833
Noca_3510
PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: tfu:Tfu_2557 putative acyl-CoA carboxylase, alpha subunit.
  
 
 0.833
Noca_0437
PFAM: acyl-CoA oxidase domain protein; acyl-CoA dehydrogenase domain protein; KEGG: tfu:Tfu_2239 hypothetical protein.
  
 
 0.832
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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