STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2189PFAM: RelA/SpoT domain protein; KEGG: lxx:Lxx23800 hypothetical protein. (223 aa)    
Predicted Functional Partners:
Noca_2392
RelA/SpoT family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.914
Noca_0274
PFAM: RelA/SpoT domain protein; KEGG: lxx:Lxx23800 hypothetical protein.
  
  
 
0.905
Noca_0164
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: rha:RHA1_ro05084 probable adenylate cyclase.
     
 0.900
Noca_0475
PFAM: Ppx/GppA phosphatase; KEGG: sco:SCO3348 putative DNA-binding protein.
     
  0.900
Noca_3020
PFAM: pyruvate kinase; KEGG: sma:SAV6217 putative pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.900
Noca_3492
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: sma:SAV3329 putative adenylate cyclase.
     
 0.900
folE
PFAM: GTP cyclohydrolase I; KEGG: sma:SAV4667 putative GTP cyclohydrolase I.
     
  0.800
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
     
  0.800
Noca_0866
PFAM: GTP cyclohydrolase II; KEGG: sma:SAV545 putative GTP cyclohydrolase II.
     
  0.800
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.