STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2282Hypothetical protein. (119 aa)    
Predicted Functional Partners:
Noca_2284
KEGG: ngo:NGO1209 DNA cytosine methyltransferase M.NgoMIII; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.859
Noca_2281
Hypothetical protein; KEGG: sus:Acid_1699 zinc finger, RanBP2-type.
   
 
 0.855
Noca_2280
PFAM: helicase domain protein; type III restriction enzyme, res subunit; restriction endonuclease; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: sus:Acid_1698 type III restriction enzyme, res subunit.
       0.785
Noca_2283
T/G mismatch-specific endonuclease; PFAM: DNA mismatch endonuclease vsr; KEGG: hch:HCH_10021 DNA G:T-mismatch repair endonuclease.
       0.773
Noca_2279
Hypothetical protein.
       0.753
Noca_2278
PFAM: sigma-70 region 4 domain protein; KEGG: sme:SMc03873 putative RNA polymerase sigma factor protein.
       0.631
Noca_2285
Hypothetical protein.
       0.510
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
      
 0.447
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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