Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Noca_2284KEGG: ngo:NGO1209 DNA cytosine methyltransferase M.NgoMIII; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (399 aa)    
Predicted Functional Partners:
Noca_2283
T/G mismatch-specific endonuclease; PFAM: DNA mismatch endonuclease vsr; KEGG: hch:HCH_10021 DNA G:T-mismatch repair endonuclease.
 
   
 0.940
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.926
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.908
Noca_4100
PFAM: amidohydrolase; Amidohydrolase 3; KEGG: mma:MM2279 N-ethylammeline chlorohydrolase.
   
 
  0.904
Noca_4106
PFAM: amidohydrolase; KEGG: aor:AO090001000163 atrazine chlorohydrolase/guanine deaminase Pfam: A_deaminase Amidohydro_3 Amidohydro_1.
   
 
  0.904
Noca_2280
PFAM: helicase domain protein; type III restriction enzyme, res subunit; restriction endonuclease; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: sus:Acid_1698 type III restriction enzyme, res subunit.
 
   
 0.891
Noca_2281
Hypothetical protein; KEGG: sus:Acid_1699 zinc finger, RanBP2-type.
 
  
 0.875
Noca_2282
Hypothetical protein.
     
 0.839
Noca_2279
Hypothetical protein.
       0.757
Noca_2278
PFAM: sigma-70 region 4 domain protein; KEGG: sme:SMc03873 putative RNA polymerase sigma factor protein.
     
 0.678
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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