STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2284KEGG: ngo:NGO1209 DNA cytosine methyltransferase M.NgoMIII; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (399 aa)    
Predicted Functional Partners:
Noca_2283
T/G mismatch-specific endonuclease; PFAM: DNA mismatch endonuclease vsr; KEGG: hch:HCH_10021 DNA G:T-mismatch repair endonuclease.
 
   
 0.940
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.922
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.910
Noca_2280
PFAM: helicase domain protein; type III restriction enzyme, res subunit; restriction endonuclease; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: sus:Acid_1698 type III restriction enzyme, res subunit.
 
   
 0.898
Noca_2281
Hypothetical protein; KEGG: sus:Acid_1699 zinc finger, RanBP2-type.
 
  
 0.871
Noca_2282
Hypothetical protein.
     
 0.859
Noca_2279
Hypothetical protein.
       0.757
Noca_2278
PFAM: sigma-70 region 4 domain protein; KEGG: sme:SMc03873 putative RNA polymerase sigma factor protein.
     
 0.671
Noca_3809
PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: sco:SCO2863 helicase.
     
 0.567
Noca_1580
PFAM: TOPRIM domain protein; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein; KEGG: mmc:Mmcs_1430 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein.
  
  
 0.555
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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