Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2479TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sma:SAV6490 hydrolase. (332 aa)    
Predicted Functional Partners:
Noca_1981
KEGG: fra:Francci3_3166 tetratricopeptide TPR_2.
  
 
 0.936
Noca_3101
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
 
 0.910
nadK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.738
Noca_2482
DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA.
     
 0.732
Noca_2478
KEGG: sco:SCO1789 hypothetical protein.
       0.648
Noca_2480
TIGRFAM: hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4 domain protein; KEGG: sco:SCO1782 putative membrane protein.
     
 0.633
Noca_2486
PFAM: NUDIX hydrolase; KEGG: tfu:Tfu_1200 conserved hypothetical protein.
  
  
 0.476
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
 0.472
cmk
Cytidylate kinase; KEGG: sma:SAV6522 putative cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
  
    0.471
Noca_2483
KEGG: rha:RHA1_ro00933 hypothetical protein.
       0.466
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.