Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_2499TIGRFAM: chorismate mutase; PFAM: Chorismate mutase of the AroH class; KEGG: sma:SAV6520 putative chorismate mutase. (128 aa)    
Predicted Functional Partners:
Noca_2500
Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: lxx:Lxx05720 prephenate dehydrogenase.
  
 
 0.986
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.962
Noca_0170
PFAM: prephenate dehydratase; KEGG: rpa:RPA3695 chorismate mutase/prephenate dehydratase.
    
 0.924
Noca_4528
Anthranilate synthase, component II; TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: cgb:cg1134 para-aminobenzoate synthase component I and II.
    
  0.906
Noca_0516
TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: tfu:Tfu_1413 isochorismate synthase.
 
  
  0.829
cmk
Cytidylate kinase; KEGG: sma:SAV6522 putative cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
       0.818
Noca_4527
PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: nfa:nfa16010 putative para-aminobenzoate synthase.
    
  0.814
der
Small GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.763
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
  
 0.736
Noca_2502
PFAM: phospholipid/glycerol acyltransferase; KEGG: sco:SCO1759 transferase.
       0.724
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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