Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Beta-lactamase domain-containing protein (230 aa)
Predicted Functional Partners:
Hypothetical protein (242 aa)
2,4-dienoyl-CoA reductase (668 aa)
NADH-flavin oxidoreductase (723 aa)
NADH-flavin oxidoreductase (699 aa)
Beta-lactamase domain-containing protein (237 aa)
Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (1019 aa)
FAD linked oxidase domain-containing protein (1000 aa)
FAD linked oxidase domain-containing protein (906 aa)