STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2600TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sma:SAV6796 uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase. (407 aa)    
Predicted Functional Partners:
Noca_0496
uroporphyrinogen-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO3317 putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase.
 
 
0.997
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.994
Noca_0354
PFAM: transcriptional regulator domain protein; Uroporphyrinogen III synthase HEM4; KEGG: sco:SCO2958 uroporphyrinogen-III synthetase.
 
 
 0.992
Noca_2892
TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_0316 precorrin-3B C17-methyltransferase region:precorrin-2 C20-methyltransferase.
  
 
 0.992
Noca_3409
TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_0316 precorrin-3B C17-methyltransferase region:precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.992
Noca_2348
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: sco:SCO6093 secreted protein.
  
 0.990
Noca_3793
PFAM: thiamineS protein; nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: pai:PAE2577 ferredoxin-nitrite reductase.
 
  
 0.982
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
  
 0.981
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.966
Noca_2351
PFAM: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region; KEGG: sco:SCO6102 putative nitrite/sulphite reductase.
 
  
 0.962
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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