STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2632TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: lxx:Lxx08260 hydrolase. (218 aa)    
Predicted Functional Partners:
Noca_2638
tRNA (adenine-58-N(1)-) methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
      0.910
Noca_2631
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
    0.855
Noca_2630
PFAM: protein of unknown function DUF75; KEGG: sma:SAV6650 hypothetical protein.
 
     0.718
Noca_3421
Kojibiose phosphorylase; PFAM: glycoside hydrolase, family 65 domain protein; glycoside hydrolase family 65, central catalytic; glycoside hydrolase family 65 domain protein; KEGG: pac:PPA1108 trehalose phosphorylase.
 
  
 0.527
Noca_2633
Hypothetical protein.
       0.489
Noca_2634
PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: rha:RHA1_ro06091 sensor kinase, two-component system.
  
    0.467
Noca_3420
TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pac:PPA1107 haloacid dehalogenase-like hydrolase.
  
   
 0.457
Noca_3183
PFAM: PfkB domain protein; KEGG: nfa:nfa28550 putative fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
    0.413
Noca_4454
PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: bme:BMEII0061 2-oxoisovalerate dehydrogenase alpha and beta subunit.
  
  
 0.411
Noca_0255
PFAM: major facilitator superfamily MFS_1; KEGG: sma:SAV5597 hypothetical protein.
  
  
 0.403
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: medium (64%) [HD]
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