STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_2687PFAM: YhhN family protein; KEGG: sma:SAV6447 hypothetical protein. (223 aa)    
Predicted Functional Partners:
Noca_2688
PFAM: aldo/keto reductase; KEGG: sco:SCO7356 oxidoreductase.
       0.757
Noca_2689
PFAM: alanine racemase domain protein; KEGG: cgb:cg2890 putative amino acid processing enzyme.
       0.757
Noca_2690
PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: rha:RHA1_ro06901 peptidylprolyl isomerase.
       0.683
Noca_2685
Hypothetical protein.
       0.551
Noca_2686
KEGG: nfa:nfa35130 hypothetical protein.
       0.551
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.511
Noca_2684
KEGG: rha:RHA1_ro02398 possible membrane protein.
       0.411
Noca_2683
PFAM: luciferase family protein; KEGG: nfa:nfa22130 putative monooxygenase.
       0.409
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.