Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Major facilitator transporter (428 aa)
Predicted Functional Partners:
Hypothetical protein (145 aa)
Regulatory protein MarR (155 aa)
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (706 aa)
Hypothetical protein (120 aa)
Cellulose synthase (669 aa)
Phospholipase D/transphosphatidylase (419 aa)
Septum site determining protein (348 aa)
Hypothetical protein (139 aa)
CHAD domain-containing protein (492 aa)
Putative spermidine synthase (262 aa)
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162 Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614