Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Noca_2836KEGG: sco:SCO2460 hypothetical protein. (145 aa)    
Predicted Functional Partners:
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
       0.781
Noca_2838
PFAM: phospholipase D/Transphosphatidylase; KEGG: tfu:Tfu_2817 phospholipase D/Transphosphatidylase.
  
    0.573
Noca_2835
PFAM: major facilitator superfamily MFS_1; KEGG: rha:RHA1_ro05089 probable MFS transporter.
       0.499
Noca_4615
KEGG: sco:SCO4674 hypothetical protein.
 
  
 0.481
Noca_2116
PFAM: DGPFAETKE family protein; KEGG: ade:Adeh_1007 DGPFAETKE domain-containing protein.
 
     0.463
Noca_3258
PFAM: GCN5-related N-acetyltransferase; KEGG: mbo:Mb0825c hypothetical protein.
 
     0.446
Noca_2107
PFAM: protein of unknown function DUF664; KEGG: sco:SCO2990 hypothetical protein.
 
     0.429
Noca_1196
PFAM: protein of unknown function DUF664; KEGG: sma:SAV7047 hypothetical protein.
 
     0.416
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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