STRINGSTRING
lig protein (Nocardioides sp. JS614) - STRING interaction network
"lig" - ATP-dependent DNA ligase in Nocardioides sp. JS614
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
ligATP-dependent DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (509 aa)    
Predicted Functional Partners:
Noca_0002
DNA polymerase III subunit beta; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (408 aa)
     
  0.944
Noca_3665
Hypothetical protein (360 aa)
 
 
  0.899
Noca_2445
Putative DNA ligase (ATP), C-terminal (326 aa)
 
 
  0.898
Noca_3006
DNA polymerase I (889 aa)
   
  0.864
Noca_2842
5’-3’ exonuclease (289 aa)
   
  0.864
Noca_1237
ATP dependent DNA ligase (304 aa)
 
 
  0.858
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5’-phosphoryl and 3’-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (752 aa)
     
 
  0.843
ku
DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5’- and 3’- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD (331 aa)
 
   
  0.839
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3’->5’ double strand exonuclease that can open hairpins. It also has a 5’ single-strand endonuclease activity (386 aa)
     
  0.827
Noca_2856
DNA primase-like protein (455 aa)
 
 
  0.821
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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