Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_2891TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: nfa:nfa50340 putative methyltransferase; Belongs to the precorrin methyltransferase family. (261 aa)    
Predicted Functional Partners:
Noca_2892
TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_0316 precorrin-3B C17-methyltransferase region:precorrin-2 C20-methyltransferase.
 
0.999
Noca_3409
TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tfu:Tfu_0316 precorrin-3B C17-methyltransferase region:precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family.
 
0.997
Noca_2893
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: tfu:Tfu_0317 precorrin-8X methylmutase.
 
  
 0.984
Noca_2879
KEGG: tfu:Tfu_0320 putative CobF protein, precorrin-6A synthase; TIGRFAM: precorrin-6A synthase (deacetylating); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
 
 0.982
Noca_2890
precorrin-6Y C5,15-methyltransferase (decarboxylating); KEGG: tfu:Tfu_0314 SAM (and some other nucleotide) binding motif; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
  
 0.979
Noca_2881
KEGG: tfu:Tfu_0310 precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase; PFAM: Precorrin-6x reductase CbiJ/CobK.
 
  
 0.965
cobB-2
Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.919
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.905
cobQ-2
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.905
Noca_3408
TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: nfa:nfa50340 putative methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 
0.901
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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