Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_2895GAF sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: GAF domain protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: rba:RB12326 sensory histidine protein kinase. (539 aa)    
Predicted Functional Partners:
Noca_1670
PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: mag:amb3735 signal transduction histidine kinase.
 
 
0.977
Noca_1977
KEGG: mca:MCA1204 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.967
Noca_1117
PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: mca:MCA1204 sensory box histidine kinase/response regulator.
 
 
0.919
Noca_1262
KEGG: bxe:Bxe_A2026 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
0.908
Noca_1748
PFAM: response regulator receiver; KEGG: dsy:DSY2891 hypothetical protein.
 
 0.881
Noca_3261
PFAM: response regulator receiver; KEGG: sco:SCO3741 putative response regulator.
 
 
 0.865
Noca_2939
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sth:STH750 two-component response regulator, probably involved in phosphate sensing.
 
 
 0.859
Noca_2050
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: rha:RHA1_ro11203 response regulator, two-component system.
 
 
 0.858
Noca_4046
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sco:SCO4230 putative response regulator.
 
 
 0.857
Noca_3500
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cjk:jk1635 response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
 
 0.853
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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