STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (366 aa)    
Predicted Functional Partners:
Noca_1429
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.994
Noca_3672
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
 
 
 0.994
Noca_3671
PFAM: Chlorite dismutase; KEGG: sma:SAV2221 hypothetical protein.
  
 0.977
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.977
Noca_2889
Protoporphyrin IX magnesium-chelatase; KEGG: tfu:Tfu_0313 Mg-chelatase subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; von Willebrand factor, type A; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase.
  
 
 0.956
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
   
 
 0.923
Noca_2314
Flavodoxin-like protein; KEGG: tfu:Tfu_3023 similar to flavodoxin.
    
 0.919
Noca_1430
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pai:PAE0596 metallo cofactor biosynthesis protein.
  
 
 0.918
Noca_4381
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cef:CE1938 putative coenzyme PQQ synthesis protein.
  
 
 0.918
Noca_0952
KEGG: rha:RHA1_ro05589 probable magnesium chelatase subunit ChlI.
  
 
 0.917
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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