Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_2935Protein of unknown function DUF59; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (377 aa)    
Predicted Functional Partners:
Noca_2933
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Polysulphide reductase, NrfD; KEGG: rha:RHA1_ro11226 probable polysulphide reductase.
  
    0.797
Noca_2932
PFAM: SirA family protein; KEGG: rha:RHA1_ro11227 hypothetical protein; Belongs to the sulfur carrier protein TusA family.
     
 0.785
Noca_2934
Formate dehydrogenase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: rha:RHA1_ro11225 hypothetical protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
       0.779
Noca_2936
PFAM: Sulfate transporter/antisigma-factor antagonist STAS; sulphate transporter; KEGG: aeh:Mlg_1668 sulfate transporter.
       0.779
Noca_2931
KEGG: rha:RHA1_ro11228 possible NADH dehydrogenase.
       0.668
Noca_4185
PFAM: lipopolysaccharide biosynthesis; KEGG: fal:FRAAL5660 putative tyrosine-protein kinase.
  
 
 0.664
Noca_2930
PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: rha:RHA1_ro11229 possible hydroxyacylglutathione hydrolase.
 
   
 0.635
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
  
  
 0.634
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.621
Noca_4219
PFAM: sugar transferase; KEGG: bth:BT0611 glycosyltransferase.
  
  
 0.531
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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