Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_30923-deoxy-D-arabinoheptulosonate-7-phosphate synthase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: tfu:Tfu_1039 phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2. (370 aa)    
Predicted Functional Partners:
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
 0.992
Noca_0170
PFAM: prephenate dehydratase; KEGG: rpa:RPA3695 chorismate mutase/prephenate dehydratase.
 
  
 0.928
Noca_3096
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: sma:SAV6086 putative 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family.
     
  0.900
Noca_2541
TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; KEGG: rha:RHA1_ro07186 transketolase; Belongs to the transketolase family.
  
 
 0.865
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
 
  
 0.841
Noca_4222
PFAM: Transketolase domain protein; KEGG: tma:TM0954 transketolase, N-terminal subunit.
 
  
  0.840
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.828
Noca_4221
Transketolase subunit B; PFAM: Transketolase, central region; Transketolase domain protein; KEGG: lmf:LMOf2365_1054 transketolase, C-terminal subunit, putative.
    
  0.815
Noca_1175
PFAM: Transaldolase; KEGG: pac:PPA0454 transaldolase.
    
 0.813
Noca_1003
PFAM: fructose-bisphosphate aldolase, class-I; KEGG: bxe:Bxe_B1334 fructose-bisphosphate aldolase.
     
  0.800
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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