STRINGSTRING
trpD protein (Nocardioides sp. JS614) - STRING interaction network
"trpD" - Anthranilate phosphoribosyltransferase in Nocardioides sp. JS614
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5’-phosphoribosyl)-anthranilate (PRA) (341 aa)    
Predicted Functional Partners:
Noca_4529
Anthranilate synthase component I/chorismate-binding protein (666 aa)
 
  0.999
Noca_4528
Anthranilate synthase, component II (187 aa)
  0.999
Noca_4527
Anthranilate synthase component I/chorismate-binding protein (437 aa)
 
  0.996
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (274 aa)
 
  0.986
trpC
Indole-3-glycerol phosphate synthase (260 aa)
 
  0.979
hisA
Phosphoribosyl isomerase A (244 aa)
   
 
  0.974
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (426 aa)
 
  0.970
Noca_3132
Hypothetical protein (139 aa)
              0.911
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (392 aa)
   
 
  0.832
Noca_3133
Hypothetical protein (328 aa)
              0.829
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
Server load: low (7%) [HD]