Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_3182Transcriptional regulator, DeoR family; PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: nfa:nfa28560 putative transcriptional regulator. (255 aa)    
Predicted Functional Partners:
Noca_3184
Fructose PTS system EIIBC or EIIC component; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit; KEGG: mmc:Mmcs_0080 phosphotransferase system, fructose IIC component; TC 4.A.2.1.4; TC 4.A.2.1.4; TC 4.A.2.1.4.
 
  
 0.993
Noca_3183
PFAM: PfkB domain protein; KEGG: nfa:nfa28550 putative fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.985
Noca_3181
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.842
Noca_3185
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: mmc:Mmcs_0079 phosphotransferase system, HPr.
 
  
 0.792
Noca_3164
Mannitol PTS system EIICBA or EIICB component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system, lactose/cellobiose-specific IIB subunit; KEGG: ppr:PBPRB0363 putative mannitol-specific IIABC component, PTS system; TC 4.A.2.1.2; TC 4.A.2.1.2; TC 4.A.2.1.2.
 
   
 0.541
Noca_3637
PFAM: FAD dependent oxidoreductase; KEGG: tfu:Tfu_2593 glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.476
Noca_2948
CoA-binding domain protein; PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: tfu:Tfu_2128 hypothetical protein.
   
   0.442
Noca_4592
PFAM: FAD dependent oxidoreductase; KEGG: sco:SCO0670 glycerol-3-phosphate dehydrogenase.
 
  
 0.442
Noca_4407
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pac:PPA2193 sodium:solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.437
Noca_3101
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
 
  
 0.420
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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