STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_3183PFAM: PfkB domain protein; KEGG: nfa:nfa28550 putative fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. (318 aa)    
Predicted Functional Partners:
Noca_3184
Fructose PTS system EIIBC or EIIC component; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit; KEGG: mmc:Mmcs_0080 phosphotransferase system, fructose IIC component; TC 4.A.2.1.4; TC 4.A.2.1.4; TC 4.A.2.1.4.
 
 
 0.999
Noca_3182
Transcriptional regulator, DeoR family; PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: nfa:nfa28560 putative transcriptional regulator.
 
  
 0.988
Noca_3164
Mannitol PTS system EIICBA or EIICB component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system, lactose/cellobiose-specific IIB subunit; KEGG: ppr:PBPRB0363 putative mannitol-specific IIABC component, PTS system; TC 4.A.2.1.2; TC 4.A.2.1.2; TC 4.A.2.1.2.
 
  
 0.977
Noca_3181
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.975
Noca_3185
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: mmc:Mmcs_0079 phosphotransferase system, HPr.
 
  
 0.958
Noca_4350
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
  
 
 0.948
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.933
Noca_3321
Transcriptional regulator, DeoR family; PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: rha:RHA1_ro11060 transcriptional regulator, DeoR family.
 
  
 0.925
Noca_3687
Transcriptional regulator, DeoR family; PFAM: regulatory protein GntR, HTH; regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: mmc:Mmcs_2425 transcriptional regulator, DeoR family.
 
  
 0.915
Noca_1066
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sma:SAV3215 putative glycerol-inducible protein.
     
 0.905
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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