STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_3198PFAM: GCN5-related N-acetyltransferase; KEGG: sma:SAV2560 putative acetyltransferase. (281 aa)    
Predicted Functional Partners:
Noca_1994
KEGG: mmc:Mmcs_3360 hypothetical protein.
  
     0.747
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.720
Noca_3444
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: tfu:Tfu_0602 hypothetical protein.
  
     0.713
Noca_2946
KEGG: sco:SCO5843 hypothetical protein.
  
     0.710
arc
Vesicle-fusing ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.689
dxr
1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
       0.660
Noca_3199
Hypothetical protein.
       0.658
Noca_3203
PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; KEGG: sma:SAV2562 putative metalloprotease.
       0.652
Noca_2578
PFAM: band 7 protein; KEGG: sma:SAV6482 secreted protein.
  
    0.637
Noca_3200
PFAM: phosphoesterase; KEGG: pac:PPA1745 hypothetical protein (phosphoesterase family).
       0.589
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.