STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Noca_3207PFAM: isochorismatase hydrolase; KEGG: eca:ECA2383 putative isochorismatase. (250 aa)    
Predicted Functional Partners:
Noca_4343
Catalase domain protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
 
 
 0.608
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.592
Noca_3206
KEGG: rso:RS05802 putative transmembrane protein.
       0.531
Noca_0516
TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: tfu:Tfu_1413 isochorismate synthase.
     
 0.526
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.494
gpsA
Glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NADP oxidoreductase, coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE, N-terminal domain protein; KEGG: sma:SAV2680 putative glycerol-3-phosphate dehydrogenase, NAD(P)H-dependent.
  
   0.478
Noca_0211
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase; PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rha:RHA1_ro04906 hypothetical protein.
  
  
 0.444
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.