Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Hypothetical protein (122 aa)
Predicted Functional Partners:
Hypothetical protein (115 aa)
Hypothetical protein (135 aa)
N-acetyltransferase GCN5 (224 aa)
Hypothetical protein (352 aa)
Hypothetical protein (65 aa)
Hypothetical protein (106 aa)
Cyclase/dehydrase (146 aa)
N-acetyltransferase GCN5 (246 aa)
Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (523 aa)
Hypothetical protein (151 aa)
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162 Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614