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Noca_3300 protein (Nocardioides sp. JS614) - STRING interaction network
"Noca_3300" - methylated-DNA--protein-cysteine methyltransferase in Nocardioides sp. JS614
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Noca_3300methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction- the enzyme is irreversibly inactivated (159 aa)    
Predicted Functional Partners:
Noca_3301
DNA-3-methyladenine glycosylase II / transcriptional regulator Ada / DNA-O6-methylguanine--protein-cysteine S-methyltransferase (494 aa)
 
 
  0.996
Noca_0664
DNA-3-methyladenine glycosylase I (197 aa)
     
  0.877
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (495 aa)
     
 
  0.699
Noca_3006
DNA polymerase I (889 aa)
     
 
  0.681
Noca_3302
Cell envelope-related transcriptional attenuator (406 aa)
              0.573
Noca_2980
Sigma-70 region 3 domain-containing protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (319 aa)
     
 
  0.561
xerD
Tyrosine recombinase XerD (318 aa)
 
 
 
  0.553
nth
Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (243 aa)
         
  0.526
Noca_3962
DNA-N1-methyladenine dioxygenase (204 aa)
   
   
  0.480
Noca_2841
Hypothetical protein (313 aa)
   
   
  0.475
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614, Nocardioides, Nocardioides JS614, Nocardioides sp. JS614
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