Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_3348Transcriptional regulator, TetR family; PFAM: regulatory protein, TetR; Tetracyclin repressor domain protein; KEGG: mmc:Mmcs_3074 transcriptional regulator, TetR family. (185 aa)    
Predicted Functional Partners:
Noca_3349
PFAM: BioY protein; KEGG: cef:CE1851 putative biotin synthase.
 
   
 0.795
Noca_3351
PFAM: cobalt transport protein; KEGG: rha:RHA1_ro05259 hypothetical protein.
 
   
 0.765
Noca_3350
PFAM: SMC domain protein; ABC transporter related; SMART: AAA ATPase; KEGG: cjk:jk1119 ABC-type cobalt transport system ATPase component.
 
   
 0.733
Noca_1138
KEGG: rxy:Rxyl_2783 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.713
Noca_1139
KEGG: gme:Gmet_0700 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
  
 0.687
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
   
 0.434
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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