Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_3389PFAM: DSBA oxidoreductase; KEGG: sco:SCO1869 hypothetical protein. (235 aa)    
Predicted Functional Partners:
Noca_3388
PFAM: iron permease FTR1; KEGG: sco:SCO2277 high-affinity iron transporter.
       0.618
ilvC-2
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.603
Noca_3387
KEGG: lxx:Lxx16280 putative iron-dependent peroxidase.
  
    0.578
Noca_2598
PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sma:SAV4764 putative NAD(P)H-dependent FMN reductase.
 
    0.516
Noca_3392
TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: tfu:Tfu_0611 acetolactate synthase, large subunit, biosynthetic type.
       0.510
Noca_3391
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: fal:FRAAL5850 acetolactate synthase III, valine-sensitive, small subunit.
       0.498
Noca_3359
PFAM: NADPH-dependent FMN reductase; KEGG: sma:SAV7045 reductase.
 
    0.451
Noca_1376
PFAM: globin; KEGG: sco:SCO2671 putative globin.
  
  
 0.428
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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