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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Noca_3403Thiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (252 aa)    
Predicted Functional Partners:
Noca_3405
TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sco:SCO2107 putative oxidoreductase.
 
 0.999
Noca_3404
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sma:SAV6094 thiamine biosynthesis ThiS.
  
 
 0.996
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.994
Noca_3401
KEGG: rme:Rmet_0169 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1.
 
  
 0.989
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
 
  
 0.989
Noca_1474
PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: sma:SAV3082 molybdopterin biosynthesis protein MoeB.
 
  
 0.983
Noca_3402
PFAM: thiamine monophosphate synthase; KEGG: pca:Pcar_0607 thiamine-phosphate pyrophosphorylase.
 
  
 0.978
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.946
Noca_0082
PFAM: FAD dependent oxidoreductase; KEGG: sma:SAV1734 oxidoreductase.
 
  
 0.825
Noca_0814
FO synthase subunit 1; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: nfa:nfa47520 hypothetical protein.
  
 
 0.771
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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