STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_3452TIGRFAM: ribonuclease, Rne/Rng family; SMART: RNA binding S1 domain protein; KEGG: sma:SAV5465 hypothetical protein. (1070 aa)    
Predicted Functional Partners:
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.927
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.837
Noca_2527
Uncharacterized P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities.
   
 
 0.820
Noca_4696
PFAM: single-stranded nucleic acid binding R3H domain protein; KEGG: sma:SAV4311 putative Jag-like protein.
   
 
 0.811
Noca_3259
RNA-binding protein (KH domain); KEGG: sma:SAV2643 hypothetical protein; Belongs to the UPF0109 family.
    
 
 0.775
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.669
Noca_1057
PFAM: PhoH family protein; SMART: Nucleotide binding protein, PINc; KEGG: sma:SAV3236 putative ATP-binding protein.
  
    0.636
Noca_2443
PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: sco:SCO1472 conserved hypothetical Sun-family protein SCL6.29c; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.632
Noca_2916
KEGG: sma:SAV2411 DNA-binding protein.
  
  
 0.632
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
    0.623
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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