Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Noca_3482PFAM: Formamidopyrimidine-DNA glycolase; KEGG: sma:SAV5427 putative DNA repair hydrolase; Belongs to the FPG family. (282 aa)    
Predicted Functional Partners:
Noca_2328
PFAM: Formamidopyrimidine-DNA glycolase; KEGG: mpa:MAP3416 probable endonuclease VIII.
  
  
 
0.926
Noca_3483
Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; KEGG: sma:SAV5426 putative ribose-5-phosphate isomerase.
 
     0.842
Noca_3484
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mmc:Mmcs_0314 alpha/beta hydrolase fold-3.
 
     0.792
Noca_2329
ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: fra:Francci3_3527 DEAD/DEAH box helicase-like.
 
  
 0.744
Noca_3481
PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: sco:SCO2624 integral membrane protein.
       0.739
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.641
Noca_3810
PFAM: BRCT domain protein; Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: tfu:Tfu_0714 exonuclease.
   
  
 0.597
Noca_3128
DNA polymerase III, epsilon subunit; KEGG: fal:FRAAL5108 putative DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Excinuclease ABC, C subunit domain protein; UvrB/UvrC protein; Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease.
  
  
 0.561
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
  
 0.558
ddl-2
D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
       0.527
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (18%) [HD]