Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_3535KEGG: sma:SAV3365 putative thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal domain. (428 aa)    
Predicted Functional Partners:
Noca_3537
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 0.999
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
  
 0.950
Noca_2919
PFAM: thymidine kinase; KEGG: sco:SCO5845 putative thimidine kinase.
 
  
 0.936
Noca_4191
PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: gbe:GbCGDNIH1_1383 blasticidin-S deaminase.
  
 
 0.932
pyrR
Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
     
 0.915
Noca_1495
N-isopropylammelide isopropylaminohydrolase; PFAM: Amidohydrolase 3; KEGG: bja:bll7276 putative cytosine deaminase.
    
 0.910
Noca_2321
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: cgb:cg0397 probable 5'-nucleotidase precursor; Belongs to the 5'-nucleotidase family.
    
 0.909
psuG
Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
    
 0.908
Noca_2322
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cjk:jk1043 putative extracellular nuclease.
    
  0.906
Noca_1242
TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sco:SCO2843 putative N-acetylglucosamine-6-phosphate deacetylase; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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