Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_3544KEGG: sma:SAV2040 putative methylmalonyl-CoA mutase, coenzyme B12-dependent alpha subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (720 aa)    
Predicted Functional Partners:
Noca_3543
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: sma:SAV2041 putative lysine arginine ornithine transport system kinase.
 
 0.999
Noca_3545
PFAM: methylmalonyl-CoA mutase; KEGG: fal:FRAAL4951 methylmalonyl-CoA mutase small subunit (MCM-beta).
 
0.999
Noca_0801
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: sma:SAV2855 lysine arginine ornithine transport system kinase.
 0.997
Noca_1798
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: sma:SAV2855 lysine arginine ornithine transport system kinase.
 0.997
Noca_2130
LAO/AO transport system ATPase; KEGG: pfu:PF1947 hypothetical protein; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase.
 0.997
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
 
0.997
Noca_1796
methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: rha:RHA1_ro01456 possible methylmalonyl-CoA epimerase.
 
  
 0.977
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
    
 0.975
Noca_0798
KEGG: sus:Acid_6472 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase.
 
0.961
Noca_0799
PFAM: cobalamin B12-binding domain protein; KEGG: pfu:PF1946 methylmalonyl-CoAmutase, subunit alpha.
  
 0.950
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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