Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_3700PFAM: protein of unknown function DUF1212; KEGG: rha:RHA1_ro04718 possible amino acid export carrier protein. (473 aa)    
Predicted Functional Partners:
Noca_3701
KEGG: sth:STH1763 hypothetical protein.
       0.585
Noca_3702
Uncharacterized enzyme; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
       0.525
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.513
Noca_3787
PFAM: Heavy metal transport/detoxification protein; KEGG: rha:RHA1_ro11206 Cu(2+)-exporting ATPase.
 
   
 0.480
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
 
     0.479
Noca_1887
TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: sco:SCO2567 integral membrane protein.
  
  
 0.471
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
    0.470
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.469
Noca_4407
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pac:PPA2193 sodium:solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.469
Noca_2013
PFAM: protein of unknown function DUF34; KEGG: rha:RHA1_ro01183 hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
    0.462
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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