Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Noca_3757L-threonine 3-dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: sco:SCO6799 threonine 3-dehydrogenase. (346 aa)    
Predicted Functional Partners:
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
 
 0.996
Noca_0979
L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; amino acid-binding ACT domain protein; KEGG: sco:SCO4962 threonine dehydratase.
   
 
 0.908
Noca_3094
L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; KEGG: sth:STH2403 threonine aldolase.
    
 0.904
Noca_1628
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: hal:VNG2430G threonine synthase.
   
 
 0.903
Noca_1745
L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
   
 
 0.903
Noca_3987
TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: tfu:Tfu_0226 threonine synthase.
   
 
 0.903
Noca_3413
8-amino-7-oxononanoate synthase; PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: fal:FRAAL6001 8-amino-7-oxononanoate synthase.
 
  
 0.696
Noca_3758
KEGG: sma:SAV2604 secreted protein.
  
    0.625
Noca_3759
Sodium/proton antiporter, CPA1 family; PFAM: sodium/hydrogen exchanger; KEGG: rha:RHA1_ro01570 Na+/H+ antiporter; TC 2.A.36.
     
 0.521
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.