STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Noca_4175PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: mpa:MAP3255 pyruvate decarboxylase; Belongs to the TPP enzyme family. (593 aa)    
Predicted Functional Partners:
Noca_3391
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein; KEGG: fal:FRAAL5850 acetolactate synthase III, valine-sensitive, small subunit.
 
 0.980
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.958
Noca_0280
(S)-2-hydroxy-acid oxidase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: nfa:nfa32960 putative L-lactate dehydrogenase.
 
 
 0.957
Noca_4176
PFAM: Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein; KEGG: rha:RHA1_ro08313 probable mandalate racemase.
 
   
 0.933
Noca_0537
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: tfu:Tfu_2674 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.926
Noca_4173
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: rha:RHA1_ro08310 short chain dehydrogenase.
 
   
 0.926
Noca_3020
PFAM: pyruvate kinase; KEGG: sma:SAV6217 putative pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.922
Noca_0113
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: tfu:Tfu_2390 malate dehydrogenase (oxaloacetate decarboxylating).
  
 
 0.920
Noca_1727
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: sma:SAV2981 putative malate dehydrogenase.
  
 
 0.920
Noca_2034
Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: amino acid-binding ACT domain protein; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rha:RHA1_ro00492 malate dehydrogenase (oxaloacetate-decarboxylating).
  
 
 0.920
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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