Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Noca_4202TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase, type I; KEGG: tfu:Tfu_0016 mannose-6-phosphate isomerase, type I. (412 aa)    
Predicted Functional Partners:
Noca_1425
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sco:SCO3028 phosphomannomutase.
  
 
 0.963
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.934
Noca_2539
PFAM: phosphoglucose isomerase (PGI); KEGG: lxx:Lxx11600 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.934
Noca_4602
Glutamine--fructose-6-phosphate transaminase; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase, isomerizing; PFAM: glutamine amidotransferase, class-II; sugar isomerase (SIS); KEGG: sco:SCO2789 glucosamine-fructose-6-phosphate aminotransferase.
    
 0.934
pfp
Pyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
  
 0.927
Noca_3184
Fructose PTS system EIIBC or EIIC component; TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIA subunit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; phosphotransferase system, EIIC; phosphotransferase system PTS, fructose-specific IIB subunit; KEGG: mmc:Mmcs_0080 phosphotransferase system, fructose IIC component; TC 4.A.2.1.4; TC 4.A.2.1.4; TC 4.A.2.1.4.
  
  
 0.922
Noca_3526
PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: sma:SAV3343 putative phosphomannomutase.
  
 
 0.919
Noca_1596
PFAM: mannose-6-phosphate isomerase, type II; Cupin 2, conserved barrel domain protein; KEGG: syn:slr0493 putative mannose-1-phosphate guanylyltransferase.
  
 
 0.916
Noca_4186
PFAM: mannose-6-phosphate isomerase, type II; Cupin 2, conserved barrel domain protein; KEGG: rpe:RPE_3497 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
  
 
 0.916
Noca_0872
PFAM: sugar isomerase (SIS); KEGG: mes:Meso_3554 sugar isomerase (SIS).
    
  0.913
Your Current Organism:
Nocardioides sp. JS614
NCBI taxonomy Id: 196162
Other names: N. sp. JS614
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